The clinical use of ketamine infusion therapy for psychiatric disorders and chronic pain management continues to evolve.
Ketamine for chronic pain: risks and benefits
The anaesthetic ketamine is used to treat various chronic pain syndromes, especially those that have a neuropathic component. Low dose ketamine produces strong analgesia in neuropathic pain states ...
Beneficial effects of ketamine in a chronic pain state with allodynia, possibly due to central sensitization
Allodynia is a well-known component of neuropathic pain resulting from injury to the nervous system.
Prolonged Analgesic Effect of Ketamine, anN-Methyl-d-Aspartate Receptor Inhibitor, in Patients with Chronic Pain
We examined the role of N-methyl-D-aspartate (NMDA) receptors in chronic (pathological) pain in humans by using the NMDA receptor antagonist ketamine as a probe.
Ketamine in Chronic Pain Management: An Evidence-Based Review
When first and second-line drugs such as opioids, anticonvulsants, or antidepressants fail to provide satisfactory analgesia for the patient with chronic pain, third-line drugs such as ketamine may provide a suitable option...