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JAMA Psychiatry. June 2014
Adriana Feder, MD1; Michael K. Parides, PhD2; James W. Murrough, MD1,3; et al
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A Randomized Clinical Trial
Important: Few pharmacotherapies have demonstrated sufficient efficacy in the treatment of posttraumatic stress disorder (PTSD), a chronic and disabling condition.
Objective: To test the efficacy and safety of a single intravenous subanesthetic dose of ketamine for the treatment of PTSD and associated depressive symptoms in patients with chronic PTSD.
Conclusions and Relevance: This study provides the first evidence for rapid reduction in symptom severity following ketamine infusion in patients with chronic PTSD. If replicated, these findings may lead to novel approaches to the pharmacologic treatment of patients with this disabling condition.
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… Symptoms in 7 patients randomly assigned to ketamine first remained significantly reduced after infusion.
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If you are currently suffering from suicidal thoughts, please contact your local crisis center or call 911.
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