At least 10-20% of the patients suffering from depression meet criteria for treatment-resistant depression (TRD)...
Ketamine therapy treatment of major depressive episodes: a systematic review
Our meta-analysis suggests that single administrations ketamine therapy are efficacious in the rapid treatment of unipolar and bipolar depression.
A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders
Several studies now provide evidence of ketamine hydrochloride's ability to produce rapid and robust antidepressant effects in patients with mood and anxiety disorders that were previously resistant to treatment.
Ketamine Infusion Therapy for Psychiatric Disorders and Chronic Pain Management
The clinical use of ketamine infusion therapy for psychiatric disorders and chronic pain management continues to evolve.
Ketamine for chronic pain: risks and benefits
The anaesthetic ketamine is used to treat various chronic pain syndromes, especially those that have a neuropathic component. Low dose ketamine produces strong analgesia in neuropathic pain states ...
Beneficial effects of ketamine in a chronic pain state with allodynia, possibly due to central sensitization
Allodynia is a well-known component of neuropathic pain resulting from injury to the nervous system.
Prolonged Analgesic Effect of Ketamine, anN-Methyl-d-Aspartate Receptor Inhibitor, in Patients with Chronic Pain
We examined the role of N-methyl-D-aspartate (NMDA) receptors in chronic (pathological) pain in humans by using the NMDA receptor antagonist ketamine as a probe.
The Correlation Between Ketamine and Posttraumatic Stress Disorder in Burned Service Members
This study investigated the prevalence of PTSD in Operation Iraqi Freedom/Operation Enduring Freedom (OIF/OEF) service members who were treated for burns in a military treatment center.
Effects of peritraumatic ketamine medication on early and sustained posttraumatic stress symptoms in moderately injured accident victims
The data provide first evidence for a modulating effect of a single-dose ketamine on the severity and duration of posttraumatic stress symptoms in accident victims.
Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder
This study provides the first evidence for rapid reduction in symptom severity following ketamine infusion in patients with chronic PTSD.